GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs9487605 | 1 | rs9487605 | chr6:111582885 | KIAA1919 | chr6:111580482-111590259:+ | -0.3 | -4.58 | 6.16E-6 | Inflammatory skin disease |
| BLCA | cis | rs9491140 | 1 | rs9491142 | chr6:124693017 | NKAIN2 | chr6:124125069-125146784:+ | 0.27 | 4.71 | 3.51E-6 | Neuroticism |
| BLCA | cis | rs950169 | 1 | rs950169 | chr15:84706461 | LOC388152 | chr15:84867600-84898920:- | -0.26 | -4.36 | 1.64E-5 | Schizophrenia |
| BLCA | cis | rs951366 | 1 | rs951366 | chr1:205685352 | PM20D1 | chr1:205797154-205819245:- | -0.21 | -4.06 | 6.05E-5 | Menarche (age at onset) |
| BLCA | cis | rs951366 | 1 | rs951366 | chr1:205685352 | RAB7L1 | chr1:205737115-205744610:- | 0.31 | 5.2 | 3.31E-7 | Menarche (age at onset) |
| BLCA | cis | rs9527 | 1 | rs9527 | chr10:104623578 | C10orf32 | chr10:104613967-104624718:+ | -0.37 | -5.72 | 2.18E-8 | Arsenic metabolism |
| BLCA | cis | rs7327064 | 1 | rs9546652 | chr13:36773131 | SOHLH2 | chr13:36742347-36871992:- | 0.32 | 4.49 | 9.57E-6 | Economic and political preferences |
| BLCA | cis | rs1577917 | 1 | rs955196 | chr6:86729951 | SNHG5 | chr6:86386726-86388451:- | 0.54 | 9.72 | 4.06E-20 | Response to antipsychotic treatment |
| BLCA | cis | rs1577917 | 1 | rs955197 | chr6:86729675 | SNHG5 | chr6:86386726-86388451:- | -0.53 | -9.41 | 4.79E-19 | Response to antipsychotic treatment |
| BLCA | cis | rs1577917 | 1 | rs955227 | chr6:86651032 | SNHG5 | chr6:86386726-86388451:- | -0.54 | -9.62 | 9.41E-20 | Response to antipsychotic treatment |
| BLCA | cis | rs9371538 | 1 | rs958283 | chr6:151887150 | C6orf97 | chr6:151815175-151942327:+ | 0.28 | 4.16 | 3.94E-5 | Bone mineral density (spine) |
| BLCA | cis | rs4141404 | 1 | rs9606830 | chr22:31717799 | C22orf30 | chr22:32072242-32146120:- | 0.21 | 4.02 | 7.07E-5 | Paclitaxel-induced neuropathy |
| BLCA | cis | rs4141404 | 1 | rs9606831 | chr22:31732512 | C22orf30 | chr22:32072242-32146120:- | 0.21 | 4 | 7.63E-5 | Paclitaxel-induced neuropathy |
| BLCA | cis | rs4141404 | 1 | rs9609254 | chr22:31705942 | C22orf30 | chr22:32072242-32146120:- | 0.22 | 4.06 | 5.86E-5 | Paclitaxel-induced neuropathy |
| BLCA | cis | rs2076028 | 1 | rs9610986 | chr22:39025277 | JOSD1 | chr22:39081549-39096459:- | -0.23 | -3.86 | 0.000135 | Resting heart rate |